3D printable optimized design for orthotic and prosthetic medical devices

Nowadays, the emergence of additive manufacturing made the high-quality manufacturing of structures with complex geometries feasible. In the field of Biomedical engineering, 3D printing techniques can be used to fabricate prosthetic and orthotic medical devices with high product quality, fast production speed, and minimized specialized manual labor.

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In-house manufactured PEEK cranioplasty implants – initial experience from Skåne University Hospital

Point of care produced implants hold great promise to improve patient care. Skåne University Hospital has recently implanted the first 3D printed implants that have been designed and manufactured on site. As far as we know this is the first time in the world where the entire process from scanning, design, manufacture, and post-processing are performed solely at the point-of-care and by the hospital.

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Stress-relieving: printing personalized cortisol for patients with adrenal insufficiency.

The treatment goal for patients with adrenal insufficiency (AI) is to mimic physiological cortisol plasma concentrations. The current cortisol replacement therapies are suboptimal due to their drug release profile, fixed-dose character and the inability to cover nocturnal cortisol plasma concentrations. There is a high inter-individual variability in the cortisol need within this patient group, which comes with the unmet need for personalized cortisol formulations. 3D printing is a suitable technology for manufacturing oral dosage forms which allows us to easily adjust the drug dose and release profile based on patient needs. The aim of this research is to develop novel tailor-made 3D printed hydrocortisone formulations covering the daily as well as nocturnal physiological cortisol plasma concentrations.

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Meeting the Process Challenges of Delivering New Therapeutics

The presentation shows a possible future development of patient experience, by Arie Platschorre, Director SIMULIA, Dassault Systemes. He is physicist by training, after obtaining a PhD in the field of Chemical Process Engineering he started working in the field of Computational Dynamics. Arie works for the SIMULIA brand of Dassault Systemes, managing a team of engineers working on simulation topics.

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3D Bioprinting Conference, 29 March

3D Bioprinting is the utilization of 3D printing and 3D printing–like techniques to combine cells, growth factors, and biomaterials to fabricate biomedical parts that maximally imitate natural tissue characteristics.

3D Bioprinting holds much promise in advancing medicine as tool to replicate cellular complexity of tissue environment, ex vivo for drug screening and as a means of engineering well-defined functional tissue units for transplantation (scaffolds, which can be used to regenerate joints and ligaments).

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3D Dental Printing Conference, 30 March

3D printing is taking its place for dental, orthodontic, stomatological and maxillofacial applications. 3D Dental Printing is part of the overall Digital dentistry which refers to the use of dental technologies or devices that incorporates digital or computer-controlled components to carry out dental procedures rather than using mechanical or electrical tools.

With 3D Printing, dental practices and prosthesis laboratories can disrupt their traditional workflow and completely dematerialise their work processes, which leads to increased efficiency, cost savings, faster production speeds and improved quality. Digitization has also allowed for better cataloguing and patient-specific care.

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3D Pharma Printing Conference, 30 March

As a new technology for the pharmaceutical industry, we foresee that 3D Printing will follow its growth path according to the following logical steps. Starting in the research laboratories (universities) with first applications in university hospitals. With that knowledge gained the next step will be the top clinical hospitals. By that time the experience both in production and compounding will reach such a level that the general hospitals and community pharmacies can start using it on a larger scale. Dependent on their level of innovation, compounding companies will join the 3D Pharma Printing bandwagon somewhere during this process.

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Beyond 3D Printing session, 30 March

The 3D Medical Printing Series covers all aspects of 3D Printing for the medical profession. But at the same time there are several technologies who can be applied in addition or next to 3D Printing, like digital twins, 3D modelling, AI, smart glasses, VR, AR and Extended reality. These new options have great impact in the daily medical way of working. One of them is that engineers are more and more involved and active in the hospital. So clinicians and engineer have to learn how to work together.

Regulation and certification plus topics like Intellectual Property are playing a crucial role for both the endusers as the developers of products and services.

This Beyond 3D Printing session will covers alle the above mentioned issues.

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Design and evaluation of 3D printed instruments for eye surgery

Additive manufacturing (AM) techniques continue to evolve pushing the boundaries of what is possible to print. For example, a strong benefit of 3D printing is that complex shapes can be printed in advanced, integrated 3D layouts without the need for assembly. However, one of the main drawbacks of 3D printing is the limited manufacturing accuracy, making it difficult to create tight tolerances in miniature high precision applications.

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