Brave new world of 3D printed organs now includes implanted ovary structures (Video)

3D printed organs

The brave new world of 3D printed organs now includes implanted ovary structures that, true to their design, actually ovulate, according to a study by Northwestern University Feinberg School of Medicine and McCormick School of Engineering.

By removing a female mouse’s ovary and replacing it with a bioprosthetic ovary, the mouse was able to not only ovulate but also give birth to healthy pups. The moms were even able to nurse their young.

The bioprosthetic ovaries are constructed of 3-D printed scaffolds that house immature eggs, and have been successful in boosting hormone production and restoring fertility in mice, which was the ultimate goal of the research. Continue reading “Brave new world of 3D printed organs now includes implanted ovary structures (Video)”

Organovo Patents Methodology for Producing Kidney Cells from Induced Pluripotent Stem Cells

UniQuest, the main technology transfer and commercialisation company of The University of Queensland (UQ), has signed an exclusive worldwide licensing agreement with Organovo Holdings, Inc. (NYSE MKT:ONVO), a three-dimensional biology company focused on delivering scientific and medical breakthroughs using its 3D bioprinting technology, to patent applications relating to methodology for producing kidney cells from induced pluripotent stem cells (iPSCs).

Professor Melissa Little and her team at UQ’s Institute for Molecular Bioscience developed a method of growing kidney tissue from iPSCs for potential use in drug screening, disease modelling and cell therapy. Continue reading “Organovo Patents Methodology for Producing Kidney Cells from Induced Pluripotent Stem Cells”

Researchers Develop 3D Printing in Gel Technique that Can Be Used in Tissue Engineering (Video)

To improve 3D printing, simply add gel. A fresh technique uses one to support complex shapes that would fall apart under their own weight in normal 3D printing.

This new-found combination of strength and delicacy will be crucial if we’re ever to print the biological structures that make up organs, blood vessels and other tissue.

The gel, which has the consistency of hand sanitiser, is made of an acrylic acid polymer. It works like a scaffold, allowing the printing of intricate patterns that would collapse without its support – such as nested Russian-doll-like structures and thin, complex branching networks. Continue reading “Researchers Develop 3D Printing in Gel Technique that Can Be Used in Tissue Engineering (Video)”

“Biofabrication: Print your heart out” – Presented by Dirk-Jan Cornelissen, Heriot-Watt University

New drugs can take more than 10 years to develop, and only around 16% of drug candidates that begin pre-clinical testing are approved for human use. This low success rate is partially due to the different responses of humans and the animal models currently used for testing. A key challenge in bioprinting has been the development of more gentle printing processes to preserve cellular functions. By encapsulating cells inside a gel, complex 3D structures can be printed with cells suspended throughout. Continue reading ““Biofabrication: Print your heart out” – Presented by Dirk-Jan Cornelissen, Heriot-Watt University”

Local start-up in Signapore unveils 3d printer that prints with living tissue

Local start-up Bio3D Technologies unveiled Singapore’s first 3D bio-printer that is able to print human cells, tissues and other biological parts. 3D printing refers to the method by which objects are created by a machine that deposits thin layers of material — typically plastic — layer by layer to form 3D shapes. Continue reading “Local start-up in Signapore unveils 3d printer that prints with living tissue”