3D-printing approaches to denture base fabrication and dental education

The use of additive manufacturing (AM) is increasingly growing in Dentistry due to the new opportunities these techniques can offer; these include custom-design, waste materials reduction, incorporation of internal structure and scaling-up possibilities, among others.

Fused deposition modelling (FDM) and stereolithography (SLA) are two of the most used AM techniques in the dental field. Each technique offers its own advantages, for example, FDM is a very cost-effective manufacturing method and SLA allows very high resolution.

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New Business Models in Healthcare: Point-of-care 3D Printing of Surgical Implants

At its current stage of development A.D.A.M. focuses on orthopedic implants and have developed two proprietary material combinations and corresponding printers. In future, we are planning to modify the extrusion printing technology to be able to print other tissues and essentially move to 4D printing.

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The Clinician Engineer Hub is partner of the 3D Medical Printing Series

The Clinician Engineer Hub was launched in 2019 in collaboration between clinicians and engineers at the Queen Elizabeth Hospital Birmingham, Imperial College London and King’s College London.
This international hub brings together the clinical and biomedical engineering fields and provides talented medical students and clinicians exposure to the world of biomedical engineering, the challenges doctors face in diagnosing and treating patients and how to potentially solve these issues with cutting edge engineering solutions.

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Industrial applications of 3D powder bed printed lactose tablets: From laboratory scale to production.

Since the approval of Spritam in 2015, various proof of concepts on 3D printed tablets have been published by the academic world. They proofed that 3D printing is a versatile technique capable of printing tablets in line with pharmaceutical standards. The next step for this technique is to convert the academic proof into industrial applications.

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Reshaping Electronics for Healthcare sector

Sustainability and health are two of the global challenges recognized by UN. Electronics is the pillar that supports the innovation in these sectors. However, current electronic components are non-biodegradable and release toxins in environment, while the implanted electronics is not compatible with soft human tissues. The aim of my research is to overcome these challenges through i) development of novel electronic material library, and ii) next-generation devices with new form factors.

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Development, characterization and encapsulation of drug loaded microgels in bioinks aimed at dentoalveolar bioprinting

Efficient delivery of growth factors and signaling molecules has an important impact on the outcome of tissue engineering strategies. However, maintaining the optimum concentration of such molecules is a challenge due to the short biological half-life on one hand, and the possibility of uncontrolled differentiation, inflammation and carcinogenicity on the other hand. While bioprinting has led to significant hope in regeneration strategies aimed at dentoalveolar region, inherent complexity and heterogeneity of these tissues highlights the demand for controlled delivery of targeted signaling molecules.

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Robotic-based in situ bioprinting

Bioprinting has provided several advantages to traditional tissue engineering approaches for fabricating scaffolds for organ/tissue regeneration thanks to a precise and controlled biomaterials processing. Nevertheless, this technology, also known as in vitro bioprinting, suffers from several limitations when considering its clinical application, such as scaffold handling difficulty, risk of contamination, need of a maturation period in a bioreactor and shape/morphology of the bioprinted construct not perfectly matching with the defect site.

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Options to implement digital printing of medicines in clinical practice

The advantages of digital printing of medicines are obvious. With this technology, it is now possible to flexibly print the individually necessary and prescribed dose on demand. Several active ingredients can also be freely combined – compounded. The number of tablets a patient takes decreases, adherence and compliance increase. The process is also much more efficient and saves resources than pressing or encapsulating drugs.

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Biofabrication and 3D Printing for Precision Healthcare

The merging of biological matter with engineering components, could transform a number of emerging fields, including regenerative medicine and bio-machine interfaces. This presentation considers my group’s recent work in biofabrication and bioprinting techniques across different length scales. Particular focus is placed on the fabrication of extracellular matrix fibre analogue, embedded 3D printing, and guided tissue assembly that could extend the feature resolution and material functionality of tissue constructs.

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3D printing for CBCT-guided Tooth Autotransplantation

In this presentation we will go through the process of CBCT-guided tooth autotransplantation starting from image pre-operative process up to post-operative follow-up and long-term outcome. Special attention will be given for the state of art 3D planning based on AI and the specific requirements of tooth replica 3D printing linking this to the treatment outcomes.

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