Biology is the most sophisticated manufacturing technology that we know of. If we could control life, we could cure disease, eliminate the organ waiting list, revert climate change and push life to other planets. However, our ability to engineer living systems has been restricted by the lack of standard tools that exist for manipulating biology. BioBots has addressed this need by creating a standard suite of digital biofabrication tools. Together with our partners and clients, we are blending biology with robotics and reimagining the modern laboratory, pushing the human race forward. Continue reading “Danny Cabrera, BioBots, Presents: “Standard Tools for Biology””
Owning a 3D printer is only the beginning of the process – what is most important is the process knowledge. Next to this, what else do we need for ramping-up to larger volumes? The answer to this question is not as obvious as you would expect. Complexity of processes, varying cycle times and traceability makes lean manufacturing within the 3D printing process industry environment a true challenge. The journey from a prototype phase to large volume production brings lots of learning opportunities and experiences to share. By remaining focused on innovative product and process development, we are determined to develop this novel technology further and to redefine the future of design. Continue reading ““Additive Manufacturing: The Next Step in Making CT Components”, Presented by Peter Hoogerhuis, Philips Healthcare”
Rapidly evolving 3D imaging, robotics, and material technologies are currently causing a paradigm shift in medicine towards personalized medicine. This lecture will give illustrate some of the current applications of 3D printing in the 3D InnovationLab of the VUmc. Furthermore, an overview will be provided of the research topics and the challenges that we face in the field of medical 3D printing. Continue reading ““The challenges of medical 3D printing”, Presented by Maureen van Eijnatten, VU University Medical Center Amsterdam”
3D printing a functional polypill: a practical manufacturing method?”, Presented by Clive Roberts, University of Nottingham. The processes used to produce tablets, the dominant form of medicine taken by patients, have changed relatively little for over a century. Whilst these approaches serve the industry and patients very well they remain limited and cannot create complex dosage forms or bespoke medications tailored for an individual or sub-population. This would be valuable in meeting therapeutic challenges and the need for personalized medicines. 3D printing, offers a route to address these issues. As an example I will show amongst other examples, a 3DP 5-drug polypill. The potential and challenges for using 3DP in the manufacture of medicines will be discussed. Continue reading “3D printing a functional polypill: a practical manufacturing method?”, Presented by Clive Roberts, University of Nottingham”
This session will provide a practical overview of the legal challenges that go along with 3D bioprinting. There are many pitfalls in 3D printing biotechnological products, e.g. the question who is the legal manufacturer, the nature of the product and the required approvals/authorizations. The presentation will address this issue as well as pros and cons of each decision. Continue reading ““3D Bioprinting and its legal challenges”, Presented by Mathias Klümper, Lützeler Klümper Rechtsanwälte”
This presentation will provide a practical overview of the regulatory framework. By way of example, it can be challenging to identify who will be considered the legal Manufacturer of a dental implant. Is it the dentist, the dental lab, the company that actually prints the implant, or the designer of the printer? The presentation will address this issue as well as pros and cons of each decision.
Three dimensional bioprinting is being applied to tissue engineering and regenerative medicine as a manufacturing tool to produce 3D tissues and organs suitable for transplantation. In the present study, we use micro-extrusion based 3D bioprinting of hydrogels embedded with genetically corrected keratinocytes from recessive dystrophic epidermolysis bullosa (RDEB) to create skin grafts. Continue reading ““3D Biofabrication of soft tissue : Material challenges” – Presented by Ahmed Aied, Centre for Biomolecular Sciences, University of Nottingham”
Advances in 3D (bio)printing need to have tailored made degradable polymers adapted to build structures mimicking our living structures.
PolyLife, a first spin-off project supported by Wallonia region, and BioMiMedics, an Interreg Meuse-Rhin project, have given us the financial tools to build a reactive extrusion platform allowing to synthesize and process degradable biocompatible polyesters in one single and continuous step. The process is rapid (minute scale), green and the equipment is GMP compliant. Continue reading ““Tailored made degradable synthetic polymers for 3D (bio)printing” – Presented by Christian Grandfils, CEIB, University of Liège”
Need for a new material – Zti–Powder® Biologically compatible, inert, stress shielding enable – to build on, new designs with better bone mechanotransduction
Adding biomolecular recognition capability to 3D printed objects: 4D printing – Presented by Céline A. Mandon, 3d.FAB – Université Lyon 1. The availability of new printing technologies and materials, in additive manufacturing processes and more specifically 3D printing, initiate profound mutation of biotechnology engineers’ way of thinking. Our group have been working on this new paradigm for the last 2 years, digging deeply into the 3D printing technologies and ink formulation to achieve complex 3D objects, composed of printed living cells evolving into human tissues or photopolymers bearing biomolecules. These 4D printed objects, by the access to unprecedented sensing layer complex geometries, generate biological diagnostic devices such as immunosensors but also enzymatically active 3D objects for biosensing and catalysis.