On Demand manufacturing of oral dosage forms: A focus on multi-material and FDM 3D printing – Presented by Mohamed Alhnan, King’s College London

Mohamed Alhnan

On Demand manufacturing of oral dosage forms: A focus on multi-material and FDM 3D printing – Presented by Mohamed Alhnan, King’s College London, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Personalised dosing is an upcoming and promising approach in drug therapy that ensures doses are tailored to an individual patient’s needs and preferences.

This can reduce the incidence of side effects and risk of overdose as pharmacodynamic and pharmacokinetic factors are able to be considered along with the age and weight of the patient. Over the years, individualising liquid oral dosage forms e.g. solutions and suspensions have been carried out by a variety of simple dosing aids e.g. calibrated spoons, droppers or syringes. Although these methods provided a low-cost solution, they were however associated with human errors during dosing. Continue reading “On Demand manufacturing of oral dosage forms: A focus on multi-material and FDM 3D printing – Presented by Mohamed Alhnan, King’s College London”

3D Medical Expo welcomes Admatec as Gold Partner

admatech

3D Medical Expo welcomes Admatec as Gold Partner

About Admatec
Admatec is dedicated to provide additive manufacturing solutions for high demanding applications and markets. With the revolutionary ADMAFLEX technology, we offer customers the ability to shape ceramics and metals from single piece to large scale productions. The ADMAFLEX process delivers strong performing materials using patented 3D printing technology. Based in the Netherlands, Admatec is located in a unique high-tech engineering environment, allowing to develop processes that include the full supply chain while recognizing the flexibility that the user expects. Continue reading “3D Medical Expo welcomes Admatec as Gold Partner”

Microgel Technology to Advance Modular Tissue Engineering – Presented by Tom Kamperman, IamFluidics

Tom Kamperman

Microgel Technology to Advance Modular Tissue Engineering – Presented by Tom Kamperman, IamFluidics

Native tissues are characterized by a complex multiscale hierarchical design. Recapitulating such complexity using a modular tissue engineering approach requires the integration of micromanufacturing techniques.

Here, I present microfluidic platforms for the production of single- and multi-cell-laden hydrogel microparticles (i.e. microgels) that act as modular tissue engineering building blocks. Continue reading “Microgel Technology to Advance Modular Tissue Engineering – Presented by Tom Kamperman, IamFluidics”

GreyMapp – Augmented Reality app for training purposes – Presented by Guido de Jong, Radboudumc – Department of Neurosurgery

Guido de Jong

GreyMapp – Augmented Reality app for training purposes – Presented by Guido de Jong, Radboudumc – Department of Neurosurgery

Neuroanatomy is a complicated subject for students, scientists and physicians which could benefit from modern three dimensional (3D) applications. One of these applications is called GreyMapp, which provides a detailed overview of the 3D anatomy of the human brain by integrating non-augmented- and augmented reality (non-AR and AR respectively).

Using GreyMapp was found to lead to a proper understanding of 3D neuroanatomy without exerting a disproportional amount of cognitive load. The cognitive load theory assumes that the human cognitive system has a limited working memory which should not be exceeded. Generally, cognitive load is divided into three categories: intrinsic, extraneous and germane cognitive load and each subset is suggested to be affected by non-AR- and AR-features. Research showed that cross-sectional learning was negatively impacted by use of GreyMapp. Continue reading “GreyMapp – Augmented Reality app for training purposes – Presented by Guido de Jong, Radboudumc – Department of Neurosurgery”

Comparing different direct metal printed resorbable medical implants – Presented by Holger Jahr, Univ. Hospital RWTH Aachen

Holger Jahr

Comparing different direct metal printed resorbable medical implants – Presented by Holger Jahr, Univ. Hospital RWTH Aachen, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Bone repair biomaterials should possess bone-mimicking fully interconnected porous structures of relevant mechanical properties. Ideally, this is combined with an appropriate biodegradation behavior to enable full regeneration and subsequent biological remodeling. Recent advances in additive manufacturing resulted in biomaterials satisfying the former two requirements, while simultaneously satisfying the latter requirement remains challenging. Continue reading “Comparing different direct metal printed resorbable medical implants – Presented by Holger Jahr, Univ. Hospital RWTH Aachen”

Bioinspired Heart Valve Prosthesis and Cellular Scaffolds by Silicone 3D Printing – Presented by Fergal Coulter, ETH Zurich – Complex Materials

Fergal Coulter

Bioinspired Heart Valve Prosthesis and Cellular Scaffolds by Silicone 3D Printing – Presented by Fergal Coulter, ETH Zurich – Complex Materials, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Artificial heart valves are highly demanded medical devices, but suffer from inferior performance compared to their biological counterparts. To tackle the poor longevity and hemodynamic behavior of many synthetic valves, an additive manufacturing platform was developed that enables the fabrication of polymer heart valves that are customizable to the patient and feature unique biologically-inspired leaflet designs.

Exploiting the shaping freedom of additive manufacturing, the synthetic valves are customized using geometries tailored to fit the anatomy of the patient. The architecture of the leaflet is designed to mimic the fiber reinforcement found in a natural valve. Continue reading “Bioinspired Heart Valve Prosthesis and Cellular Scaffolds by Silicone 3D Printing – Presented by Fergal Coulter, ETH Zurich – Complex Materials”

A Precision Workflow for Clinical Bioprinting – Presented by Derek Mathers, Advanced Solutions Life Sciences

Derek Mathers

A Precision Workflow for Clinical Bioprinting – Presented by Derek Mathers, Advanced Solutions Life Sciences, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Current bioprocess manufacturing focuses on biologic replacement therapies and monoclonal antibodies. We are at the beginning of a new wave of therapies wherein the cell is the therapy.

We have seen large investments and regulatory approvals for T-cell therapies but if we only address immunotherapy, we will miss the most significant opportunity of today’s medical society: the opportunity to manufacture patient-specific replacement parts.

We present here the vision of a workflow to address the need to generate replacement structures, tissues, and eventually organs that are living, bespoke, autologous, and regulated. Continue reading “A Precision Workflow for Clinical Bioprinting – Presented by Derek Mathers, Advanced Solutions Life Sciences”

Core-shell printing of Alginate-CMC scaffolds for engineering of tubular tissues – Presented by Marko Milojevic, University of Maribor

Marko Milojevic

Core-shell printing of Alginate-CMC scaffolds for engineering of tubular tissues – Presented by Marko Milojevic, Faculty of Medicine, University of Maribor, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Vascularization is still a major challenge preventing the tissue engineering of thick tissues and many strategies are being explored for in vitro manufacturing of channel networks with appropriate form, perfusion volume, chemistry and mechanics.

Core-shell three dimensional (3D) printing allows direct fabrication of channel structures with a liquid core and a stable shell, which is cross-linked at the interface. Continue reading “Core-shell printing of Alginate-CMC scaffolds for engineering of tubular tissues – Presented by Marko Milojevic, University of Maribor”

3D medical printing: throw the dice! – Presented by Ernst-Jan Louwers, Louwers IP|Technology Advocaten

Ernst-Jan Louwers

3D medical printing: throw the dice! – Presented by Ernst-Jan Louwers, Louwers IP|Technology Advocaten at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

New technologies like bioprinting and 3D printing of medical devices, braces etc. may lead to shifting positions and reponsibilities. Players like hospitals may turn into factories but do not realise their changed position.

Ernst-Jan Louwers will discuss the rules of the game in the highly regulated medical market, paradigm shifts and concerns in supply chain, warranties, liabilities and IP. Continue reading “3D medical printing: throw the dice! – Presented by Ernst-Jan Louwers, Louwers IP|Technology Advocaten”

3D printing of dental applications on an industrial production level from a digital service provider point of view – Presented by Ludwig Schultheiss, INFINIDENT Solutions

Ludwig Schultheiss

3D printing of dental applications on an industrial production level from a digital service provider point of view – Presented by Ludwig Schultheiss, INFINIDENT Solutions, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

INFINIDENT Solutions is one of the pioneers in the field of additive manufacturing of dental prostheses. For more than ten years the use of additive technologies, such as laser sintering and stereolithography are part of its service portfolio.

The technologies used at INFINIDENT enable the daily production of individual restorations and model castings out of non-precious metals, as well as different types of dental models based on acrylate resins for dental technicians in Europe.

The presentation will provide an inside view into the world of digital industrial production of dental applications and discuss the benefits and challenges of 3D printing. Continue reading “3D printing of dental applications on an industrial production level from a digital service provider point of view – Presented by Ludwig Schultheiss, INFINIDENT Solutions”