Multimaterial and Multiscale Biofabrication of 3D in vitro models of complex tissues – Presented by Giovanni Vozzi, University of Pisa

Multimaterial and Multiscale Biofabrication of 3D in vitro models of complex tissues – Presented by Giovanni Vozzi, University of Pisa, at the 3D Medical Conference, which will take place on 30-31 January 2018 at MECC Maastricht, The Netherlands. Read the interview

A biological tissue is a composite material with “bottom-up” hierarchical structure that is closely related to its heterogeneous function. The extracellular matrix modulates biochemical and biophysical signalling, and its rigidity is an important microenvironmental parameter that regulates the spatiotemporal dynamics of intercellular signalling. For this reason, many studies are focused on fabricating scaffolds processed at multiple scales with structural and mechanical properties that are optimal for eliciting specific response or mimic those found naturally. These scaffolds have to present large surface areas that have appropriate topology and biochemical cues (e.g, ligands) at the nanoscale for tissue adhesion, while also exhibiting integral porosity to allow for the exchange of molecules that maintain cellular function.

In this talk, the use of a multiscale and multimaterial process will be presented to develop 3D in vitro model that can mimic the 3D complexity of natural tissue. These novel 3D in vitro models can be used for the study of physio-pathological condition and for the analysis of effects on cell activities of different biomolecule and/or drugs.

About Giovanni Vozzi
Giovanni Vozzi was graduated in Electronic Engineering in 1998 at the University of Pisa. In 2002 got the PhD in Bioengineering at Polytechnic of Milan. He is Associate Professor of Bioengineering at the Department of Ingegneria dell’Informazione of University of Pisa He is member of Directors board of International Society for Biofabrication, of IEEE and Of National Group of Bioengineering. His research interests are: 1)development of new micro and nanofabrication techniques; 2) development of bioreactors; 3) mechanical, chemical and topological characterization of biomaterials; 4) development of cell models through the fusion of Automatic Controls principles and of cell biochemical reactions.

About University of Pisa – Research Center “E. Piaggio”
The Research Center “E.Piaggio” of University of Pisa is one of the oldest interdisciplinary research and technology transfer centers in Europe, devoted to the training of personnel for careers in Research and Development. The Center has paved the way for the convergence of minds by bringing together scientists from different fields of knowledge. The Center provides the state of the art research and training facilities for young scientists from all over the world, offering researchers from different backgrounds the opportunity to combine their expertise and know how to generate high-quality, innovative and translational advances in technological, scientific and humanistic fields.

Below you can watch a video of the SQPR (SQqueeze PRessure) bioreactor, an innovative system for long term cell-culture and tissue engineering developed and patented at the Interdepartmental Research Center “E. Piaggio” — Faculty of Engineering, University of Pisa.

3D Medical Printing ConferenceAbout 3D Medical Conference
On January 30-31, 2018, MECC Maastricht, The Netherlands, will host a two-day event focused on 3D Medical Printing. Each day has different topics.

Day 1, Jan 30:

Day 2, Jan 31:

The audience, a mix of academics, medical professionals, business, technology, regulation and creatives, will get an excellent overview and insight in the medical tech developments from different perspectives.

Combination tickets are available and can be purchased on any of the conference websites.

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