Individualized bone replacement parts by hybrid ceramic manufacturing

tassilo moritz

by Tassilo Moritz, Fraunhofer Institute for Ceramic Technologies and Systems IKTS

Recently, the innovative Freeze Foaming technique has been developed by Fraunhofer IKTS which allows producing an open cellular structure with a bimodal pore size distribution. In in-vitro tests foams made of tricalciumphosphate and hydroxyapatite have been investigated with mice stem cells showing that the cells proliferate and start to differentiate and to form collagene structures.

Continue reading “Individualized bone replacement parts by hybrid ceramic manufacturing”

Nanofiber technologies for improving the biological compatibility of metal implants

marek pokorny

by Marek Pokorny, Contipro a.s.

In the current project we deal with surface modification of implants for large joints, which are prepared by traditional and additive technologies. Czech private company Prospon s.r.o., material scientists from the Academy of Sciences of the Czech Republic, and we from private company Contipro a.s. as specialists in surface treatment of 3D surfaces with the help of an electrostatic field are involved in the project.

In my presentation I would like to draw attention to the importance of surface treatment of 3D implants intended for pharmacy. A surface layer of a metal implant affects its acceptance by the human body. The surface treatment enhances metal implant properties e.g. its biocompatibility, enhance a cell adhesion and proliferation, reduce inflammatory responses, and facilitate integration between the implant and surrounding tissues.

Continue reading “Nanofiber technologies for improving the biological compatibility of metal implants”

Voxel Printing for Surgery

Nicholas Jacobson

by Nicholas Jacobson, MIX Design

Voxel printing is the ability to vary material point by point across a 3d printed model. This allows us to better model changes in tissue and structure in fine detail. I will be showing our latest work using voxel printed model in the OR for Neurology, Hapatobiliary transplantation, and Cardiology. Finally I’ll be covering some of our latest custom tools for modeling and 3d printing.

Continue reading “Voxel Printing for Surgery”

3D Printing with High Perfomance Polymers for Implants and other Medical Products

stefan leonhardt

by Stefan Leonhardt, Kumovis

We at Kumovis developed a specialized 3d-printing system including clean-room technology. It is capable of processing high performance polymers like PEEK, PEKK, Ultem or PPSU. Furthermore, a special focus is set on degradable polymers.

At the conference we will present our technology and show results regarding achievable clean-room class inside our 3d-printing system. Also first clinical use-cases like using our technology for the lower jaw reconstruction will be presented.

Continue reading “3D Printing with High Perfomance Polymers for Implants and other Medical Products”

Disruptive Multi Material 3D Technology

Rene van der Meer

by Rene van der Meer, Lake3D

The start-up Lake3D wants to develop the first 3D Dental printer based on Multi Material 3D inkjet. It uses printheads suited for high temperatures and high viscous materials that make it possible to jet class II medically certified materials that are already being used in traditional 3D (SLA) printers. Combining different materials makes it possible to print objects with the right colour, transparency and mechanical characteristics. This might bring a revolution in 3D printing as colour did in television.

Continue reading “Disruptive Multi Material 3D Technology”

Simufact Engineering will exhibit at 3D Medical Conference

hexagon simufact

Simufact Engineering is Gold Partner of the 3D Medical Expo during 3D Medical Conference 2020

About Simufact Engineering

Simufact Engineering – an MSC Software company – is a global operating software company providing process simulation products and services to manufacturing industries.

Today, after nearly 25 years of developing and supporting simulation solutions for the design and optimization of manufacturing techniques in metal processing, the Hamburg (Germany) headquartered company has established as one of the leaders in this business area.

Continue reading “Simufact Engineering will exhibit at 3D Medical Conference”

Digital Drug Manufacturing – towards truly personalized drug delivery

Anton Aulbers

by Anton Aulbers, TNO

One of the challenges of the pharma industry is the need for faster development and production of drug dosage forms for ever smaller target groups. TNO has built up a solid position and reputation in the field of 3D printing for the food industry.

Making use of this know-how base TNO is now together with partners, initiating innovations, in the pharma value chain, to unlock the potential of 3D Pharma printing as an enabling technology for cost effective small scale drug product manufacturing, dose personalization, multi-drug combinations and tailored release profiles.

Continue reading “Digital Drug Manufacturing – towards truly personalized drug delivery”

Using digital twins to design 3D printed implants for skeletal tissue engineering

Liesbet Geris

by Liesbet Geris, University of Liege

One of the major challenges in tissue engineering and an essential step towards successful clinical applications is the translation of biological knowledge on complex cell and tissue behavior into predictive and robust engineering processes. Computational modelling can contribute to this, among others because it allows to study the biological complexity in a more quantitative way. Computational tools can help in quantifying and optimizing micro-environmental signals to which cells and tissues are exposed and in understanding and predicting the biological response under different conditions.

A wide variety of model systems has been presented in the context of tissue engineering ranging from empirical models (data-driven) over gene network models to mechanistic models (hypothesis-based), targeting processes at the intracellular over the cellular up to the tissue level. Each model system has its own benefits and limitations which delineate the context in which it can be used. Whereas mechanistic models are used as in silico tools to design new therapeutic strategies and experiments, empirical models are used to identify, in large data sets, those in vitro parameters (biological, biomaterial, environmental) that are critical for the in vivo outcome.

Continue reading “Using digital twins to design 3D printed implants for skeletal tissue engineering”