Inkjet-printed “Mini-Pills” for preclinical studies

Anastasia Zakharyuta

by Anastasia Zakharyuta, Post-Doctoral Researcher, Boehringer Ingelheim Pharma GMBH Co & KG

This presentation will focus on the development of formulations for pre-clinical studies is attempted in two different forms, namely basic and complex release solid dosage formulations. The former dosage is aimed to provide an alternative to suspensions, as to minimize variability by improving stability and repeatability of the routine formulations.

The latter provides the complex formulations at the early stage of rodent studies, by combining different formulation mechanisms. The different design for such formulations is feasible with regard to the desired release profile and administration route.

Herein, printing procedures are established for solid dosage fabrication, through incorporation of a number of low molecular weight biodegradable polymers via piezo-actuated inkjet printing.

Continue reading “Inkjet-printed “Mini-Pills” for preclinical studies”

3D printing: when a disruptive technology meets the legal perspective – Stampa 3D: quando una tecnologia dirompente incontra la prospettiva legale

Licia Garotti

by Licia Garotti, Partner of the law firm Gattai, Minoli, Agostinelli & Partners

The 3D printing has been acclaimed as a disruptive technology, which is changing the scenario in many different sectors.

The most revolutionary implementation has been developed in life science and healthcare, leading to legal implications which are far from ordinary.

From the responsibility arising from the use of product obtained with 3d print, to commercial and data protection features, touching the aspects of intellectual property, a state of the art of the mostly relevant legal profiles will take shape.

Continue reading “3D printing: when a disruptive technology meets the legal perspective – Stampa 3D: quando una tecnologia dirompente incontra la prospettiva legale”

3D printing in Medicine. A new competence of Radiology?

Carmelo G. Puglisi

presented by Carmelo G. Puglisi, Medical Doctor, Radiologist, Arnas Garibaldi Catania

I will talk about the new scenarios in Medicine, focusing on the all-days cases that 3d printing applied to clinical needs can resolve. Will expose also my experience as a Medical Doctor , Radiologist, using 3D printing in selected cases for the pre-surgery planning .

program: https://3dmedicalconference.com/program/

Continue reading “3D printing in Medicine. A new competence of Radiology?”

M3dRES – Additive Manufacturing for Medical Research and Education – Presented by Ewald Unger, Medical University Vienna

Ewald Unger

M3dRES – Additive Manufacturing for Medical Research and Education – Presented by Ewald Unger, Medical University Vienna, Center for Medical Physics and Biomedical Engineering, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

In the last few decades Additive Manufacturing (AM), colloquially known as 3D printing, has been rapidly adopted as a cutting-edge technology gaining more importance in medical applications. Novel ideas for medical treatments using AM has reached maturity in this new field of research, with an increasing number of publications and the establishment of educational programmes in Universities across the globe. The uniqueness of AM in producing customized models with high accuracy allows planning and training of critical operations and traching of advanced medical strategies for a better patient support. Continue reading “M3dRES – Additive Manufacturing for Medical Research and Education – Presented by Ewald Unger, Medical University Vienna”

A Precision Workflow for Clinical Bioprinting – Presented by Derek Mathers, Advanced Solutions Life Sciences

Derek Mathers

A Precision Workflow for Clinical Bioprinting – Presented by Derek Mathers, Advanced Solutions Life Sciences, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Current bioprocess manufacturing focuses on biologic replacement therapies and monoclonal antibodies. We are at the beginning of a new wave of therapies wherein the cell is the therapy.

We have seen large investments and regulatory approvals for T-cell therapies but if we only address immunotherapy, we will miss the most significant opportunity of today’s medical society: the opportunity to manufacture patient-specific replacement parts.

We present here the vision of a workflow to address the need to generate replacement structures, tissues, and eventually organs that are living, bespoke, autologous, and regulated. Continue reading “A Precision Workflow for Clinical Bioprinting – Presented by Derek Mathers, Advanced Solutions Life Sciences”

Core-shell printing of Alginate-CMC scaffolds for engineering of tubular tissues – Presented by Marko Milojevic, University of Maribor

Marko Milojevic

Core-shell printing of Alginate-CMC scaffolds for engineering of tubular tissues – Presented by Marko Milojevic, Faculty of Medicine, University of Maribor, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Vascularization is still a major challenge preventing the tissue engineering of thick tissues and many strategies are being explored for in vitro manufacturing of channel networks with appropriate form, perfusion volume, chemistry and mechanics.

Core-shell three dimensional (3D) printing allows direct fabrication of channel structures with a liquid core and a stable shell, which is cross-linked at the interface. Continue reading “Core-shell printing of Alginate-CMC scaffolds for engineering of tubular tissues – Presented by Marko Milojevic, University of Maribor”

3D printing of dental applications on an industrial production level from a digital service provider point of view – Presented by Ludwig Schultheiss, INFINIDENT Solutions

Ludwig Schultheiss

3D printing of dental applications on an industrial production level from a digital service provider point of view – Presented by Ludwig Schultheiss, INFINIDENT Solutions, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

INFINIDENT Solutions is one of the pioneers in the field of additive manufacturing of dental prostheses. For more than ten years the use of additive technologies, such as laser sintering and stereolithography are part of its service portfolio.

The technologies used at INFINIDENT enable the daily production of individual restorations and model castings out of non-precious metals, as well as different types of dental models based on acrylate resins for dental technicians in Europe.

The presentation will provide an inside view into the world of digital industrial production of dental applications and discuss the benefits and challenges of 3D printing. Continue reading “3D printing of dental applications on an industrial production level from a digital service provider point of view – Presented by Ludwig Schultheiss, INFINIDENT Solutions”

Need a new skull or mandible? 3d print it! – Presented by Jules Poukens, University Hasselt & Leuven

Jules Poukens

Need a new skull or mandible? 3d print it! – Presented by Jules Poukens, Cranio-maxillofacial Surgeon, Zuyderland Medical Center / The Netherlands, Lecturer-Researcher, University Hasselt and Leuven, Belgium, at the 3D Medical Conference 2019.

Patients in the cranio-maxillofacial clinic often present with serious, complex, and potentially life- threatening or life-limiting medical conditions (e.g. tumor, trauma, aggressive osteomyelitis). Available treatments may not always give satisfactory results for patients and doctors. Therefore, complex problems ask for new solutions.

An emerging technique in the medical field is Computer Aided Design (CAD) , Computer Aided Manufacturing (CAM) by 3D printing. For successful implementation of CAD-CAM technology in the clinical practice doctors, dentists and engineers need to work together and share their expertise.

This intense cooperation leads to 3D printing of custom patient specific implants. 3D printed implants are used for the treatment of skull defects, temporo-mandibular joint replacement and world’s first 3D printed entire mandible replacement implant.

Clinical cases will be highlighted. Continue reading “Need a new skull or mandible? 3d print it! – Presented by Jules Poukens, University Hasselt & Leuven”

3DPrint2Fiber – Combining the strength of carbon fibre with the versatility of 3D printing – Presented by Benjamin Els, Mecuris

mercuris

3DPrint2Fiber – Combining the strength of carbon fibre with the versatility of 3D printing – Presented by Benjamin Els, Mecuris, at the 3D Medical Conference, on January 30-31, 2019, MECC Maastricht, The Netherlands

Current methods of manufacturing custom ankle foot orthotics can be a time and labor intensive process. This project aims to create a solution for difficulties experienced within the current AFO creation process, while leaving the customisation within the experienced hands of orthopaedic technicians. To achieve this, Mecuris along with its various partners, are developing a process which combines the versatility of 3D scanning and – printing with the superior material properties of carbon fiber – a combined process which aims to provide orthotic technicians with superior products and less effort involved in manufacturing. Continue reading “3DPrint2Fiber – Combining the strength of carbon fibre with the versatility of 3D printing – Presented by Benjamin Els, Mecuris”

Researchers create 3D printed stem cell-infused scaffolds for spinal cord repair

3D printed stem cell

Researchers create 3D printed stem cell-infused scaffolds for spinal cord repair

University of Minnesota researchers have broken new ground in the rapidly advancing field of 3-D printing: creating stem cell-infused scaffolds that could be implanted in spinal cords to repair nerve damage.

The technology has existed for years to print plastic implants containing live cells. But the challenge was to do so in a way that would allow sensitive “neuronal” stem cells to survive the printing process so they can repair nerve damage after transplant. Continue reading “Researchers create 3D printed stem cell-infused scaffolds for spinal cord repair”