Comparing biocompatibilities of 3D-printed absorbable metal implants

Holger Jahr

by Holger Jahr, Uniklinik RWTH Aachen

Additively manufactured absorbable porous metal implants possess promising mechanical and degradation properties in vitro and thus hold potential to meet various clinical applications. A reliable evaluation of these novel implants, however, requires an improved predictability of their biocompatibility and in vivo degradation characteristics from in vitro results. Current pre-clinical in vitro evaluation of medical devices still occurs under largely static culture conditions, while dynamic interstitial fluid flow regulates clearance of degradation products in vivo.

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Comparing different direct metal printed resorbable medical implants – Presented by Holger Jahr, Univ. Hospital RWTH Aachen

Holger Jahr

Comparing different direct metal printed resorbable medical implants – Presented by Holger Jahr, Univ. Hospital RWTH Aachen, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Bone repair biomaterials should possess bone-mimicking fully interconnected porous structures of relevant mechanical properties. Ideally, this is combined with an appropriate biodegradation behavior to enable full regeneration and subsequent biological remodeling. Recent advances in additive manufacturing resulted in biomaterials satisfying the former two requirements, while simultaneously satisfying the latter requirement remains challenging. Continue reading “Comparing different direct metal printed resorbable medical implants – Presented by Holger Jahr, Univ. Hospital RWTH Aachen”

Additive manufacturing (resorbable) metal implants for orthopaedic applications – Presented by Holger Jahr, UK RWTH Aachen

Holger Jahr

Additive manufacturing (resorbable) metal implants for orthopaedic applications – Presented by Holger Jahr, UK RWTH Aachen, at the 3D Medical Conference, which will take place on 30-31 January 2018 at MECC Maastricht, The Netherlands. Read the interview

In our increasingly elderly population the number of large bone defect treatments is increasing. Due to lifestyle changes, traumatic knee injuries in young adults is also an increasing phenomenon and strongly associated with premature osteoarthritis. Additively manufactured implants seem to offer attractive and personalized solutions for both. Designing complex micro-architectures with advanced nano-topographies is crucial to creating state-of-the-art meta-biomaterial properties to improve their bone tissue regeneration potential and anti-microbial properties. While a plethora of materials exist, metals appear to be beneficial for certain applications. The best implant, however, may be the one that does its job and disappears. Continue reading “Additive manufacturing (resorbable) metal implants for orthopaedic applications – Presented by Holger Jahr, UK RWTH Aachen”

Additive manufacturing to revolutionise personalized regenerative medicine – Holger Jahr, UK RWTH Aachen

Holger Jahr

Additive manufacturing to revolutionise personalized regenerative medicine – Holger Jahr, UK RWTH Aachen

Holger Jahr is Secretary-General of the European Orthopaedic Research Society and director of the Orthopaedic research lab at the University Hospital of the RWTH Aachen. He holds an associate professorship in Experimental Orthopaedics and honorary appointments with the Maastricht UMC+ and TU Delft. His research focuses on regenerative biomaterials for musculoskeletal disorders. In 2017, he received the Klee Family Innovation Award for his work on lattice structured 3D-printed metal implants. On January 31, 2018, he will speak during the 3D Medical Printing Conference in Maastricht about Additive manufacturing (resorbable) metal implants for orthopaedic applications

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