Design and characterization of a novel 3D printed pressure-controlled drug delivery system – Presented by Julius Krause, University of Greifswald

Julius Krause

Design and characterization of a novel 3D printed pressure-controlled drug delivery system – Presented by Julius Krause, University of Greifswald, at 3D Medical Conference 2019

The aim of the present work was to explore the feasibility of 3D printing via fused deposition modeling (FDM) in the manufacturing of a pressure-controlled drug delivery system.

Eudragit® RS, a brittle polymer with pH-independent solubility, was chosen to be a suitable excipient for the 3D printing of a pressure-sensitive, capsule-like dosage form.

A self-constructed piston extruder was used for hot melt extrusion (HME) of filaments made from Eudragit® RS that could be used for 3D printing. Continue reading “Design and characterization of a novel 3D printed pressure-controlled drug delivery system – Presented by Julius Krause, University of Greifswald”