Boosting bone regeneration: Additive manufacturing of continuous gradient scaffolds using functional composite materials

Maria Camara Torres

by Maria Camara Torres, MERLN Institute for Technology Inspired Regenerative Medicine

Bone fractures, infection related debridement, or tumor resections can lead to large or non-union bone defects, where the normal process of bone regeneration is interrupted and prevent bone self-healing ability. By using scaffolds, tissue engineering aims at providing structural and biological support to regenerate bone. While additive manufacturing (AM) enables to fabricate patient specific 3D scaffolds with optimal mechanical properties and architecture, there is still a need of technologies and materials that allow to fabricate functional scaffolds for regenerating tissues in their complexity.

Continue reading “Boosting bone regeneration: Additive manufacturing of continuous gradient scaffolds using functional composite materials”

Bioprinting of tissues and organs – Presented by Carlos Mota, Maastricht University

carlos mota

Bioprinting of tissues and organs – Presented by Carlos Mota, Maastricht University, at the 3D Medical Conference, which takes place on January 30-31, 2019, at MECC Maastricht, The Netherlands.

Bioprinting technologies are a group of computer-driven systems used to manufacture three-dimensional (3D) tissue and organ-like constructs. These 3D structures are normally manufactured with bioinks where the combination of specific cells and biomaterials is tuned according to the aimed tissue or organ.

At the MERLN institute, we are using different bioprinting techniques, namely extrusion, droplet-on-demand and microfluidics to develop tissue implants and organ models. Some examples of the tissue implants already developed are constructs for long bone defects and cardiac patch. For the long bone implant, novel alginate-based bioinks have been developed and combined with human periosteum-derived cells. Continue reading “Bioprinting of tissues and organs – Presented by Carlos Mota, Maastricht University”

Designing biomaterials for tissue regeneration – Presented by Sandra Camarero-Espinosa, MERLN

Sandra Camarero-Espinosa,

Designing biomaterials for tissue regeneration – Presented by Sandra Camarero-Espinosa, MERLN Institute for Technology Inspired Regenerative Medicine, at the 3D Medical Conference, on January 30-31, 2019, MECC Maastricht, The Netherlands

On the past decades materials sciences have experienced a boom with increasing knowledge being generated on nanotechnology and on the control and design of materials properties. Despite the great advances in the field and the exploitation of this knowledge in applications such as electronics, optics, photonics and drug delivery systems, little has been translated into tissue engineering (TE) applications. Continue reading “Designing biomaterials for tissue regeneration – Presented by Sandra Camarero-Espinosa, MERLN”