3D-Bioprinting holds much promise in advancing medicine as tool to replicate cellular complexity of tissue environment ex vivo for drug screening and as a means of engineering well-defined functional tissue units for transplantation.Continue reading “What is the current 3D Bioprinting landscape?”
by Silvia Faré, Associate Professor, Politecnico di Milano – Dept Chemistry, Materials and Chemical Engineering
Smart hydrogels reversibly change their properties when exposed to an external driven force as pH or temperature variation (1). Methylcellulose (MC) is a polysaccharide derived from cellulose and when dissolved in aqueous solvents it forms reverse thermo-responsive smart hydrogels that undergo a sol-gel transition when heated (2).
At the same time, another smart material is represented by gelatin that needs to be crosslinked for biomedical applications. Crosslinked gelatin bulk scaffolds, 3D printed structures and microspheres can be obtained by tuning its crosslinking kinetic, innovatively without the need of post-curing or external treatments to stabilize the crosslinked printed hydrogel structure (3).Continue reading “3D printing of thermo-responsive hydrogels”