3D printed silk ‘micro-rockets’ could deliver medicines through your body
Sheffield engineers make major breakthrough in developing silk ‘micro-rockets’ that can be used safely in biological environments.
By using an innovative 3D inkjet printing method, researchers from Chemical and Biological Engineering at the University of Sheffield have taken the biggest step yet in producing microscopic silk swimming devices that are biodegradable and harmless to a biological system.
This means that these devices have the potential to be used in the human body in the future in applications such as drug delivery and locating cancer cells.
This new technique allows the researchers to use safer, non-toxic materials, meaning the micro-rockets will not cause harm or injure any living tissue or biological environment. This is a significant development as previous devices have been expensive to produce, complicated to manufacture and made from polystyrene beads, carbon nanotubes or metals which have to be covered in a catalyst layer (such as platinum) to be able to swim successfully, these devices are usually less friendly to the biological environment they are placed in.
The rockets are just 300 microns in length and 100 microns in diameter, the thickness of a single human hair, and create their own thrust, allowing them to ‘swim’ through any bio fluid containing the fuel.
A silk microrocket ‘swimming’ in an aqueous hydrogen peroxide solution:
Source: sheffield.ac.uk; image: Shutterstock via biosciencetechnology.com