From small scale to large scale – Pharma-grade filament manufacturing and thermal analysis of the printing process – Presented by Julian Quodbach, Heinrich Heine University Düsseldorf at The 3D Medicine & Pharmaceutical Printing Conference which will take place on Feb 01, 2017 at MECC Maastricht in The Netherlands.
Pharmaceutical fused deposition modeling requires feedstock material based on pharma-grade polymers. In literature, either non-pharma-grade polymers are chosen due to their easy processability and/or small-scale extruders were used for filament production that cannot produce substantial amounts of feedstock material. In this presentation, large scale fabrication of Eudragit RL based, drug loaded filaments with a continuously running twin-screw-extruder is presented. The mechanical properties of these filaments are compared to commercial specimen. In a second part, a thermal imaging analysis of the printing process is shown. It is demonstrated that the thermal load is significantly lower than process settings suggest.
About Julian Quodbach
Julian Quodbach obtained his PhD at the University of Düsseldorf under the supervision of Prof. Dr. Peter Kleinebudde. He then transferred to the working group of Prof. Dr. Jörg Breitkreutz where he is currently supervising 3 PhD students working on additive manufacturing of pharmaceutical dosage forms and related topics.
Heinrich Heine University Düsseldorf is one of the younger higher education institutions in the state of North Rhine-Westphalia – founded in 1965. Since 1988 our university has carried the name of one of the city’s finest sons. Today around 30,000 students study at a modern campus under conditions ideally suited to academic life.
As a campus university where everything is close together, all buildings including the University Hospital and the specialised libraries are easily reachable. Our university departments enjoy an excellent reputation due to an exceptionally high number of collaborative research centres. Moreover, the state capital Düsseldorf provides an attractive environment with a high quality of life.