New 3D Bioprinter for Tissue Engineering and Organ Regeneration

With the new 3D Bioprinter, the research group of Professor Paul Gatenholm at the Department of Chemical and Biological Engineering exploits new possibilities of tissue engineering and organ regeneration. ​Professor Paul Gatenholm’s research has gained a lot of attention lately, both in newspapers and on television. A quick interview..

How does bioprinting work?
3D Bioprinter is a robotic arm which can dispense fluids with high resolution. We talk about 10 micrometers. Bioprinter has several printing heads with which it can dispense high viscous suspensions, extrude hydrogel and dispense cell suspension. It is designed to work in sterile environment so it can handle human cells in the same operation when the hydrogel which will support human cells will be dispensed. It can handle several different cell types at the same time. 3D Bioprinter is thus able to produce a scaffold with microarchitecture corresponding to microstructure of tissue which is going to be reproduced.

How can it be used in Life Science research?
We can produce model tissues which will function as the whole organ. Those model organs are called organoids. We have prepared model of adipose tissue which can be used to screen drugs for treatment of obesity. The challenging organ is liver and we are working to prepare miniature liver using human hepatocytes. The advantage is that the cells can be used from patient who has disease and thus lead to development of patient specific drugs. The big advantage is also to omit animal study and in early stage test on human organoid without entering clinical trials. … (Read more)

Source:AZom.com

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