Researchers Develop 3D Printing in Gel Technique that Can Be Used in Tissue Engineering (Video)

To improve 3D printing, simply add gel. A fresh technique uses one to support complex shapes that would fall apart under their own weight in normal 3D printing.

This new-found combination of strength and delicacy will be crucial if we’re ever to print the biological structures that make up organs, blood vessels and other tissue.

The gel, which has the consistency of hand sanitiser, is made of an acrylic acid polymer. It works like a scaffold, allowing the printing of intricate patterns that would collapse without its support – such as nested Russian-doll-like structures and thin, complex branching networks.

This complexity is important. Researchers have long wanted to 3D-print whole human organs, but these need fine, dividing systems of blood vessels to supply them with oxygen and nutrients. The new technique enables printing at the right dimensions to do this, creating structurally sound spheres as thin as two sheets of paper and strands about 10 times thinner by embedding the objects in gel.

A hitch in using traditional 3D printing to create the kinds of structure found in our organs is that they collapse long before being finished. Printing into supportive gel gets around that challenge, preventing the creations from sagging or buckling before they solidify. The gel is supportive because it is essentially a solid, says Thomas Angelini at the University of Florida in Gainesville, who led the research.

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